Meet the modern tablet coater designed to tackle your coating challenges
The pharmaceutical industry has witnessed incredible technological advancements over the years, with tablet-coating technology being no exception. What began as a simple effort to enhance the aesthetic appeal and palatability of tablets has evolved into a sophisticated process that plays a critical role in drug delivery.
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The strategic advantage of HPMC capsules in modern pharmaceutical manufacturing
Capsules represent one of the most versatile dosage forms in pharmaceuticals, offering exceptional flexibility in content delivery - from powders and pellets to semisolids and liquids. The versatility of capsules as a dosage form has made them an indispensable part of pharmaceutical formulation development. Traditionally, gelatin has been the primary material for capsule manufacturing, valued for its non-toxic nature, robustness, and compatibility with high-speed manufacturing processes. Gelatin capsules typically disintegrate within 5-10 minutes in biological media and demonstrate rapid in vitro dissolution for immediate-release solid oral dosage forms, indicating satisfactory in vivo performance. These characteristics have been key factors in their widespread adoption across the pharmaceutical industry.
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The evolution and future of inhalation drug delivery systems
The rising global burden of respiratory diseases has made effective pulmonary drug delivery systems increasingly important. The field of inhalation drug delivery has emerged as a crucial area of medical innovation, offering unique advantages over traditional oral administration methods. This article explores the current landscape of inhalation drug delivery systems, their mechanisms, and their future potential.
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Navigating the complexities of bilayer tablet manufacturing
Bilayer tablets have gained prominence as a sophisticated oral drug delivery system, offering a versatile approach to managing complex therapeutic needs. By combining two distinct layers within a single dosage form, these tablets allow for the co-administration of drugs with differing release profiles or chemically incompatible properties.
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Overcoming key pharmaceutical formulation challenges with liquid-filled hard capsules
Liquid-filled capsules are an innovative drug delivery system, particularly valuable for pharmaceuticals with challenging formulation requirements. These capsules can enhance bioavailability, improve dosing accuracy and product stability making them an effective solution for a range of formulation issues. This article explores common formulation challenges that liquid-filled capsules address and discusses critical considerations for formulating these capsule products.
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Should you bottle it up or blister it?
Pharmaceutical packaging for oral solids plays a critical role in ensuring product integrity and safety. Traditionally, bottles have been the primary choice for packaging tablets and capsules. However, the past few decades have seen blister packaging emerge as a strong alternative, particularly for its suitability for unit-dose products. While both bottles and blister packs offer unique benefits, blister packaging provides significant advantages in terms of product protection, patient compliance, and cost effectiveness. Here, we’ll explore why blister packaging is often the superior choice over bottles, focusing on quality, patient safety, regulatory compliance, and overall cost-effectiveness.
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Optimising investment in hot-melt granulation the smart way
Hot-melt granulation has emerged as a transformative process in pharmaceutical manufacturing, offering distinct advantages over conventional wet and dry granulation techniques. Recent technological advancements in equipment design and the growing emphasis on continuous manufacturing have further expanded the application scope of melt granulation.
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